The Megakaryocytes in Idiopathic Thrombocytopenic
نویسندگان
چکیده
An adult girl, robust, without manifest cause, was attacked recently, towards the period of her menses, with a sudden severe hemorrhage from the nose, with bright but foul blood escaping together with a bloody vomiting of a very thick extremely black blood. Immediately there appeared about the neck and on the arms, spots partly black, partly violaceous or purple, such as are often seen in malignant smallpox moreover the number of the spots increasing and surrounding completely both of the eyes, the back of the nose and the skin around the mouth and chin, with a livid black color, like marked from bruises.
منابع مشابه
Neutropenia Following Intravenous Immunoglobulin Therapy in Pediatric Patients with Idiopathic Thrombocytopenic Purpura
Background: Children with idiopathic thrombocytopenic purpura who are treated with intravenous immunoglobulin therapy might experience a decline in their absolute neutrophil count. The aim of this study was to investigate the incidence of neutropenia following intravenous immunoglobulin therapy in children with idiopathic thrombocytopenic purpura undergoing intravenous immunoglobulin therapy. ...
متن کاملComparison of the Quality of Life among Patients with Idiopathic Thrombocytopenic Purpura and Healthy People in Isfahan, Iran
Background: Quality of life has been used as an important tool to understand illnesses impact in recent decades. Idiopathic thrombocytopenic purpura is a chronic disease which affects the individuals’ quality of life. The present study was conducted to compare the quality of life among idiopathic thrombocytopenic purpura patients’ with healthy people. Patients and Methods: This was a descri...
متن کاملThe relation of thrombokinetics to bone marrow megakaryocytes in idiopathic thrombocytopenic purpura (ITP).
In 23 patients with untreated idiopathic thrombocytopenic purpura (TP), the relation of thrombokinetics to quantitative determinations of megakaryocytes in bone marrow sections was studied. The megakaryocytes were classified into maturation stages, and platelet sizes were determined. Megarkaryocyte number and volume per microliter of bone marrow were significantly higher in ITP as compared to c...
متن کاملUltrastructural study shows morphologic features of apoptosis and para-apoptosis in megakaryocytes from patients with idiopathic thrombocytopenic purpura.
To investigate whether altered megakaryocyte morphology contributes to reduced platelet production in idiopathic thrombocytopenic purpura (ITP), ultrastructural analysis of megakaryocytes was performed in 11 ITP patients. Ultrastructural abnormalities compatible with (para-)apoptosis were present in 78% +/- 14% of ITP megakaryocytes, which could be reversed by in vivo treatment with prednisone ...
متن کاملThe Relation of Thrombokinetics to Bone Marrow Megakaryocytes in Idiopathic Thrombocytopenic Purpura (
In 23 patients with untreated idiopathic thrombocytopenic purpura (ITP), the relation of thrombokinetics to quantitative determinations of megakaryocytes in bone marrow sections was studied. The megakaryocytes were classified into maturation stages, and platelet sizes were determined. Megakaryocyte number and volume per microliter of bone marrow were significantly higher in lIP as compared to c...
متن کاملBernard-Soulier syndrome or idiopathic thrombocytopenic purpura: A case series
Background: Bernard-Soulier syndrome (BSS) is a rare, autosomal recessive platelet function disorder which is commonly mistaken for idiopathic thrombocytopenic purpura (ITP).The report includes seven cases of BSS that have been diagnosed and treated as ITP for a long time. Methods: Between 2006 and 2016, data of seven BSS patients who have long been diagnosed and treated as ITP were collected ...
متن کامل